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Lilly to spend up to $7.8 billion to acquire Centessa, a maker of experimental sleep disorder drugs

Centessa is one of several companies working on a new class of drugs to treat narcolepsy, a condition that makes it difficult for people to stay awake.

6 April 2026 at 09:02 pm
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Lilly to spend up to $7.8 billion to acquire Centessa, a maker of experimental sleep disorder drugs

Lilly to Spend Up to $7.8 Billion to Acquire Centessa, a Maker of Experimental Sleep Disorder Drugs

Lilly, a leading pharmaceutical company, has announced plans to acquire Centessa, a smaller biotech firm specializing in experimental sleep disorder drugs, in a deal valued at up to $7.8 billion. This acquisition marks a significant strategic move for Lilly, which aims to expand its portfolio in the area of sleep medicine and address the growing need for treatments for conditions such as narcolepsy.

Centessa is one of several companies working on a new class of drugs to treat narcolepsy, a condition that makes it difficult for people to stay awake. Narcolepsy affects approximately 1 in 2,000 people globally, and current treatments often rely on stimulants, which can have side effects and limited effectiveness. The acquisition of Centessa allows Lilly to tap into cutting-edge research and development in this promising area, potentially leading to more effective therapies for patients suffering from sleep disorders.

The deal, which is expected to be completed in the first half of 2024, reflects Lilly's commitment to investing in innovative solutions for sleep disorders. The company has been actively seeking to strengthen its presence in this market, recognizing the unmet medical needs and the potential for growth in the sleep medicine sector. By acquiring Centessa, Lilly gains access to Centessa's research pipeline, including its lead compound, CESP101, which is in clinical trials for the treatment of narcolepsy.

The acquisition also brings Lilly closer to other key players in the sleep disorder space, such as Helsinn Pharmaceuticals and Jazz Pharmaceuticals, which have been aggressively pursuing treatments for narcolepsy and other sleep-related conditions. This move positions Lilly as a major player in the race to develop effective therapies for these debilitating disorders.

The terms of the acquisition, which includes a combination of cash and stock, have been agreed upon by both parties. Lilly has stated that it intends to maintain Centessa's research and development operations, ensuring continuity in the development of its experimental drugs. This commitment is crucial, as it allows Centessa's team of experts to continue their work on innovative treatments without disruption.

The acquisition of Centessa is not without its challenges. Regulatory approvals and potential antitrust concerns may pose obstacles to the deal's completion. However, Lilly has a track record of successfully navigating complex regulatory environments, and the company is confident that it will overcome any hurdles.

The deal also highlights the growing importance of sleep medicine as a focus area for pharmaceutical companies. With an aging global population and increased recognition of the impact of sleep on overall health, the demand for effective treatments for sleep disorders is expected to rise. By acquiring Centessa, Lilly is positioning itself to meet this growing demand and capitalize on the potential for significant revenue growth in this area.

In conclusion, Lilly's acquisition of Centessa represents a strategic and ambitious move into the sleep disorder drug market. With a focus on developing innovative treatments for narcolepsy and other sleep-related conditions, the deal underscores the company's commitment to addressing unmet medical needs and expanding its global influence in the pharmaceutical industry. As the acquisition progresses, patients and healthcare professionals will be watching closely to see how these developments translate into improved treatments and better outcomes for those suffering from sleep disorders.

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